Browsing by Author "GEBREMARIAM MEBRAHTU"

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    EVALUATION OF ANALGESIC, CLINICO-PHYSIOLOGICAL AND HEMATOLOGICAL EFFECTS OF CAUDAL EPIDURAL LIDOCAINE AND XYLAZINE IN MALE CATLLE CALVES IN MEKLLE, TIGRAY, ETHIOPIA
    (Mekelle University, 2024-02-25) GEBREMARIAM MEBRAHTU
    An experimental study was performed from Juley 2023 to February 2024 to evaluate the anesthetic, clinico-physiological, and hematological effects of lidocaine and xylazine as epidural analgesia in the local breed of male cattle calves. A total of twelve clinically healthy calves aged 7 to 10 months and weighing between 55 and 78 kg were randomly divided into three groups ( L, X, and C) comprising four animals each. Group C was assigned as a control, group L and X received 2% lidocaine (0.22mg/kg) and xylazine (0.03mg/kg) respectively. The agents were administered at the caudal epidural space (the first intercoccygeal epidural space /Co1–Co2/). Analgesia was tested using a pin-prick test on the skin of the tail, perineum, anus, and the upper parts of the hind limbs. Epidural anesthesia and analgesia were produced in all-male cattle calves treated with lidocaine and xylazine. The time of onset and duration of anesthesia was recorded. Clinicophysiological parameters were recorded at 0, 10, 20, 30, 60, 90, and 120 minutes, and hematological parameters were also recorded at 0, 30, 60, 90 and 120 minutes. The onset of analgesia was faster in Group L (4.25±0.65 minutes) compared with that of Group X (11.34±1.65 minutes). Epidural administration of xylazine produced a significantly longer duration of analgesia (138.50±1.29 minutes) than that produced by epidural injection lidocaine (68.75±1.71minutes). The heart rate and respiration rate nonsignificantly change in Groups L and X, whereas rectal temperature decreased significantly in those groups. The hematological parameters decreased in groups treated with lidocaine and xylazine. There were no significant changes in heart rate, respiration rate, rectal temperature, and hematological parameters in Group C. The overall observation on clinico-physiological and hematological parameters showed that both anesthesia and analgesia induced some alterations in their values but, these alterations were found temporary without any clinical significance. Moreover, lidocaine and xylazine were safely used for caudal epidural analgesia taking into account the anesthetic, clinico-physiological and, hematological parameters in male cattle calves. These findings indicate that lidocaine and xylazine are an economical and useful approach for epidural anesthesia