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    MAGNITUDE AND ASSOCIATED FACTORS OF POST TUBERCULOSIS COMPLICATIONS AMONG PATIENTS ATTENDING IN CHEST CLINIC AT AYDER COMPREHENSIVE SPECIALIZED HOSPITAL.
    (Mekelle University, 2024-09-01) MERHAWI GEBRIHANS
    Background: Pulmonary tuberculosis remains an important public health problem globally and one of most common infectious disease. A past history of pulmonary tuberculosis (TB) is a risk factor for longterm respiratory impairment. Post-TB lung dysfunction often goes unrecognized, despite its relatively high prevalence and its association with reduced quality of life. There is no data on the prevalence and associated factors of post tuberculosis complications in Ethiopia, particularly Tigray region. Objective: To determine the magnitude and associated factors of post tuberculosis complications among patients attending chest clinic at Ayder Comprehensive Specialized Hospital. Method: This was a retrospective, cross-sectional analysis of patients registered in a clinical database, charts and log book at the chest clinic of Ayder Comprehensive Specialized Hospital from September, 2022 –September, 2024 GC. The data was collected from the charts and smart care using prepared form. Analysis was made on SPSS 27 software. Descriptive statistics, frequency and proportions were utilized for Socio-demographic and clinical variables and bivariate and multivariate analyses were done to explore association between the dependent and independent variables. Results: a total of 367 TB treated patients were reviewed at the chest clinic of Ayder Comprehensive Specialized Hospital. Among these patients, 41.4 %( 152) had a diagnosis of post TB complications/ sequelae by imaging (chest CT and/ or chest x-ray), which was commented on by radiologist and pulmonologist. Statistical analysis indicated that older age(AOR: 4.401, 95% CI: 2.193-8.832, p =0.000), rural residency(AOR: 2.290, 95% CI: 1.424-3.681, P =0.001), smoking history(AOR=3.509, 95% CI: 1.810- 6.803, p-value=.000)and prolonged duration of TB illness (AOR:2.00,95% CI: 1.260-3.175, P= 0.003) were significantly associated with higher risk of post TB complications. Conclusion and recommendation: This study shows high-rate post TB complications/sequelae. Older age, rural residency, smoking and prolonged duration of tuberculosis illness significantly increase the riskx of developing these sequelae. These findings highlight the need for targeted follow up care and rehabilitation.