College of Health Sciences
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Item DETERMINANTS OF PREMATURE RUPTURE OF MEMBRANES AMONG PREGNANT MOTHERS ATTENDING PUBLIC HOSPITALS OF CENTRAL ZONE, TIGRAY, ETHIOPIA, 2024; UNMACHED CASE-CONTROL STUDY(Mekelle University, 2025-01-28) GEBREMARIAM KIFLEBackground: Premature rupture of membranes is a condition in which the fetal membranes rupture before the onset of labor and after 28 weeks of gestational age. It complicates 5-10% of all pregnancy, and it is an important cause of perinatal, neonatal, and maternal morbidity and mortality both in developed and developing countries. Though some studies were conducted in Ethiopia on the determinants of premature rupture of membranes there was limited study in the Tigray region, particularly in the study area Objective: To identify determinants of premature rupture of membranes among pregnant mothers admitted to public hospitals in the Central Zone, Tigray, Ethiopia,2024 Methods: A hospital based unmatched case-control study design was conducted from August 1 to September 30, 2024, in public hospitals of Central Zone of Tigray, Ethiopia. All cases admitted at the time of data collection were included until the desired sample size was met, and controls were selected by systematic random sampling. Data were collected using a structured and pre-tested questionnaire by trained midwives then data were entered into Epi Data Version 4.7 and exported to Statistical Package for Social Sciences Version 27. Logistic regression was employed to identify determinant variables. Variables with a p value of less than 0.05 with a 95% confidence interval were used as a statistically significant association in a multivariable logistic regression. Result: A total of 363 participants (121 cases and 242 controls) were included in the study. Rural residence (AOR=2.17,95 % CI: 1.31-3.59, p-value=0.003), having multiple fetus (AOR=2.44,95% CI: 1.01-5.89, p-value=0.047), history of Premature rupture of membrane (AOR=2.76,95% CI: 1.42-5.38, p-value=0.003), and Mid-upper arm circumference <23cm (AOR=2.79,95% CI: 1.59-4.89, p-value=0.001) were identified as determinants of premature rupture of membrane. Conclusion and recommendation: The identified determinants of premature rupture of membranes were rural residence, multiple gestation, history of Premature rupture of membrane, and Mid-upper arm circumference <23 cm. Therefore, pregnant women who live in rural areas, have multiple pregnancy and had history of premature rupture of membranes should be well followed up during pregnancy. Moreover, early nutritional screening, counseling and intervention should be strengthened during prenatal care.