College of Health Sciences
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Item FERTILITY DESIRE AND ITS ASSOCIATED FACTORS AMONG WOMEN ATTENDING ANTIRETROVIRAL THERAPY AT PUBLIC HOSPITALS IN MEKELLE, TIGRAY, ETHIOPIA, 2024: CROSS SECTIONAL STUDY(Mekelle University, 2025-02-25) SOLOMON TEKLUBackground: Fertility desire is defined as having motivation or intention to give birth by individuals in their future life irrespective the number of children. Fertility desire has undesirable effect on the transmission of human immunodeficiency virus to the partner due to unsafe sex, vertical transmission to the children and there will be also disagreement with the strategies developed for elimination of human immunodeficiency virus/acquired immunodeficiency syndrome in countries including Ethiopia. Objective: To assess the prevalence of fertility desire and its associated factors among women attending antiretroviral therapy at public hospitals in Mekelle, Tigray, Ethiopia, 2024. Methods and Materials: Institutional based cross-sectional study was conducted among 355 women and participants were selected using systematic random sampling method. The data were collected from August 1, 2024 to August 30, 2024 using pre-tested and interviewer administer questionnaire. Few variables were recorded from participant’s card. The data were analyzed using statistical package for social science version 27. Binary logistic regression method of analysis was used. All variables with P-value <0.25 in bivariate were included in the multivariable binary logistic regression analysis. The strength of the association was interpreted using an adjusted odds ratio with its 95% confidence interval. Statistically significant variable was declared at P-value < 0.05. Finally, the data were presented with texts, tables, figures, and graphs. Results: This study included 355 women, of them 345(97.2%) responded to the study. The prevalence of fertility desire was 182(52.8%, 95% CI: 46.6%-59.1%). Being single 69.3% (AOR: 0.307, 95% CI: O.111-0.84), being widowed 91% (AOR: 0.09, 95% CI: 0.038-0.214), being divorced 76.7% (AOR: 0.233, 95% CI: 0.109-0.497), number of women’s child 50.8% (AOR: 0.492, 95% CI: 0.382-0.632) and knowledge of women on prevention mother to child transmission 24.5% (AOR: 0.755, 95% CI: 0.608-0.938) were negatively associated with fertility desire. Conclusion and recommendation: This study revealed that more than half of participants had fertility desire and factors associated with it were marital status, number of women’s child, knowledge of the women on prevention mother to child transmission. All stakeholders should take into account the prevalence of fertility and its associated factors while serving the women living with human immunodeficiency virus and counsel the women to decrease their interest on the number of children and promote knowledge on the prevention of mother to child transmission.Item MAGNITUDE AND ASSOCIATED FACTORS OF LOW BIRTH WEIGHT AMONG NEWBORNS DELIVERED IN PUBLIC HOSPITALS OF TIGRAY DURING CONFLICT TIME.(Mekelle University, 2025-06-21) SAMSON HADUSHBackground: Birth weight is a critical determinant of perinatal survival and significantly influences infant morbidity and mortality. Low birth weight remains a serious global health issue, particularly in developing countries like Ethiopia, where research on low birth weight and its determinants is limited. This lack of data hampers efforts to address the underlying factors contributing to low birth weight and improve maternal and child health outcomes. The war in Tigray has disrupted healthcare services, potentially exacerbating the challenges associated with maternal health that leads low birth weights. Understanding the factors contributing to LBW will help to identify the impact of conflict on maternal and infant health and ensure that vulnerable populations receive the necessary support. Thus, the objective of this study aimed at identifying the magnitude and associated factors of LBW among newborns delivered at public health facilities in Tigray, Ethiopia Method: A Hospital based cross-sectional study design was applied from November 2024 – December 2024. A total of 540 newborn birth records were selected using systematic random sampling technique, and data was collected using data kobo tool. Six BSc degree holders were employed for data collection and the data collection period was entirely supervised by one masters’ degree holder and myself. Data was entered into Epi info 7, then exported to SPSS version 23. Binary logistic regression model was used to assess the associated factors of low birth weight. The results are presented as crude odds ratios (P<0.25) and adjusted odds ratios (AOR) (P<0.05) together with their corresponding 95% confidence intervals. Results: A total of 540 maternal cards were reviewed during the study period, with 95.8% rate of complete cards. In logistic regression model, significant association was found with Unplanned Pregnancy (AOR=10.4, 95% CI 5.10 - 21.26), No Antenatal care follow up (AOR=3.6, 95% CI 1.35 – 9.837), Gestational age <37 weeks (AOR=6.5, 95% CI 3.32 – 12.67), Obstetric complication (AOR=2.5, 95% CI 1.24 – 4.97), Medical complication (AOR=2.9, 95% CI 1.02 – 8.32), Maternal Anemia (AOR=3.3, 95% CI 2.37 – 46.49.26) and Acute malnutrition (AOR=2.8, 95% CI 1.31 – 9.94). Conclusion: The study finding indicated that a significant number of newborns measured low birthweight. The study identified factors such as pregnancy plan, ANC follow up, Obstetric and Medical condition during pregnancy, maternal acute malnutrition, Maternal Anemia and Gestational Age had significant association. Based on study findings, I recommend Tigray government and regional health bureau to make sure accessible health care system and advocating to nongovernmental organizations to support in recovering health care system which is destructed, Health care providers to counsel and provide comprehensive health care, particularly during pregnancy and before pregnancy.Item MAGNITUDE AND ASSOCIATED FACTORS OF TB/HIV CO INFECTION AMONG HIV INFECTED PATIENTS ATTENDING IN MEKELLE PUBLIC HOSPITALS, TIGRAY, ETHIOPIA 2024/25(Mekelle University, 2025-05-21) KAHSU TSEGAYIntroduction: -Tuberculosis is a contagious air born disease caused by Mycobacterium tuberculosis species and the leading causes of morbidity and mortality among people living with HIV/AIDS worldwide accounting for about 25% of all causes of the deaths. HIV infected clients are more susceptible to Tuberculosis infection. The World Health Organization Global Tuberculosis report of 2018 estimated that 10.0 million new cases of Tuberculosis occurred in 2017, of which over 82% of Tuberculosis deaths occurred in low- and middle-income countries. Evidence from this study helps to develop policies that address TB and HIV in an integrated, cost-effective manner and more efficient use of funds and resources. Objective: - The aim of this study was to assess the Magnitude and its associated factors of TB/ HIV co-infection among HIV infected patients in public hospitals of Mekelle, Tigray, Ethiopia 2025. Methods and materials: - Institutional based cross-sectional study was conducted and the period of data collection was from November to December 2024 G.C among ART patients. Systematic sampling technique was used to select 394 participants from the total source population. Data were collected using a pretested, interviewer, administered questionnaire and reviewing the medical record of the patient (CD4 cell count, hemoglobin level, BMI, WHO clinical stage, diagnosis of opportunistic infections, and TB). Data collection tool was pretested in 5% of total sample size in Wukro General Hospital. Data were coded and entered in to Epi data and was exported to statistical package for social science version 27 for statistical analysis. Descriptive statistics were performed. Both bivariate and multivariable logistic regression analyses were used to determine the association between independent variable and dependent variable. Variables having p value less than 0.25 in the bivariate analysis were exported in to multivariate logistic regression in multivariate logistic regression, p value <0.05 with 95% confidence interval (CI) was considered statistically significant. The Hosmer- Lemeshow goodness-of-fit model coefficients tests procedure was used to test for model fitting. Result – The magnitude of TB/ HIV co-infection was 18.8% and confidence interval (18.761 – 18.839). Marital status being widowed (AOR and 95% CI 0.238 (0.062, 0.903), hemoglobin level less than 11 (AOR and 95% CI 4.937 (1.884, 12.943), low CD4 count (200 cells mm3) (AOR and 95% CI 3.405 (1.174, 9.872), suspected TB patients in the household AOR and 95% CI 2.59 (1.026, 6.562) opportunistic infection without TB AOR and 95% CI (6.169 (2.272, 16.747), ambulatory AOR and 95% CI 22.906 (4.918,106.697), Bedridden AOR and 95% CI 11.436 (3.461, 37.79), poor drug adherence AOR and 95% CI 3.767 (1.389, 10.221), alcohol consumption AOR and 95% CI 15.129 (5.232, 43.748), raw/un cook foods consumption AOR and 95% CI 3.255 1.094, 9.682. were significant determinants of TB/HIV co-infection among HIV clients. Conclusion and recommendation The prevalence of tuberculosis among ART patients was high and this study indicated that marital status, hemoglobin level, CD4 count, presence of suspected TB patients in the household, presence of opportunistic infection without TB, functional status, drug adherence, alcohol consumption, utilization of raw/un cook foods were found significantly associated with TB/HIV co-infection. Providing counseling and health education regarding drug adherence, alcohol consumption and chat chewing to ART patients, and government should give priority on TB/ HIV confection.Item DETERMINANTS OF SUCCESSFUL VAGINAL BIRTH AMONG MOTHERS WITH ONE PREVIOUS CAESAREAN SECTION IN PUBLIC HOSPITALS MEKELLE, TIGRAY, ETHIOPIA 2024: CASE CONTROL STUDY(Mekelle University, 2025-01-28) HADIS DERBEWBackground: The World Health Organization says that 10-15% of babies should be born by C-section in hospitals. But in many countries, including Ethiopia, more babies are born by Csection. This can have bad effects on health and the economy. Having a vaginal birth after a previous C-section (VBAC) is usually safe and a good way to have fewer C-sections. Even though VBAC is successful 60-80% of the time, fewer mothers are trying to have a vaginal birth after a previous C-section, and the number of C-sections is going up. In Tigray have not been studied using case control study approaches on determinants of successful VBAC. So, this study aimed to identify determinants of successful VBAC at public hospitals in Mekelle town. Objective: To assess determinants of successful vaginal birth among women with one previous caesarean delivery in Mekelle public hospitals in 2024. Methods: Institutional based unmatched case control study was conducted in Mekelle public Hospitals from August 1, - September 30, 2024. A total of 194 study participants were included, of which 65 were cases and 129 were controls with cases to controls ratio of 1: 2. Systematic random sampling for controls and cases were selected consecutively. Data were collected using a structured and pre-tested questionnaire then data was entered to Epidata version 4.7 to be cleaned and coded, and exported to statistical package for social science version 27 for analysis. Bivariate, followed by multivariate analysis, were conducted with 95% CI and p-value <0.05 to identify factors associated with successful vaginal birth after cesarean delivery. Result: urban residence (AOR = 2.50, 95%CI: 1.13-5.55), history of SVD (AOR= 2.47, 95%CI: 1.10-5.51), cervical dilatation at admission > 4 cm (AOR = 2.36, 95%CI: 1.01-534), occiputo- anterior position (AOR = 9.69, 95%CI: 2.15-5.55) were determinants significantly associated with successful vaginal birth after previous cesarean section. Conclusion and recommendation: The study shows that urban residence, history of SVD, cervical dilatation at admission > 4 cm, occiputo- anterior position were associated with successful vaginal birth after previous cesarean section. Women live in rural area and cervical dilatation <4 cm at admission health care provider encourage, create awareness and counseled to delivery virginally after c/s. Women with a history of cesarean section should be counseled and encouraged to delivery vaginally as it is not contraindicated.Item TREATMENT OUTCOME AND ASSOCIATED FACTORS AMONG UNDER-FIVE CHILDREN WITH SEVERE ACUTE MALNUTRITION WHO ARE ADMITTED IN STABILIZATION CENTER OF PUBLIC HOSPITALS, IN EASTERN ZONE OF TIGRAY, ETHIOPIA, 2024.(Mekelle University, 2025-01-28) HAGOS MEHARIBackground: Globally, it is estimated that there are nearly 20 million children who are severely acutely malnourished. Undernutrition accounts for 45% of child mortality under the age of five, stunting still affects more than 5.4 million Ethiopian children. Researches are limited on treatment outcomes among sever acute malnutrition children in Tigray, Therefore, this study has the potential to fill this gap by providing evidences on treatment outcomes and associated factors among under-five children admitted in a stabilization center. Objective: The aim of the study is to assess treatment outcome and associated factors among children under-five with severe acute malnutrition who are admitted in a stabilization center, in public hospital in eastern zone of Tigray region 2024. Methods: A health facility-based cross-sectional study was done in 6 public hospitals of eastern zone of Tigray. The total sample size was 347 which were proportionally allocated for each hospital based on the estimated monthly case admission and participants were selected from each hospital using simple random sampling method. A pretest was done on 5% of the sample size in Kuiha hospital. In the Bivariate analysis variables with p-value < 0.25 were a candidate for the multivariable logistic regression analysis and statistical significance was declared at a p-value of <0.05. Result: Among 347 children, 70.3%, 19%, 6.3% and 4.6% of the cases were cured, died, transferred out and defaulters respectively. Children with better appetite upon admission (AOR = 3.849, 95% CI: 1.183–12.523), higher admission weight (AOR = 3.998, 95% CI: 2.022, 7.908), greater weight gain during treatment (AOR = 1.601, 95% CI: 1.096–2.339) and longer hospital stays (AOR = 1.222, 95% CI: 1.021–1.463) were associated with good treatment outcome. Conversely, the presence of fever at admission (AOR = 0.343, 95% CI: 0.152–0.772) was negatively associated with treatment success. Conclusions and Recommendations: Appetite upon admission, admission weight, fever, weight gain, and length of stay were significantly associated with treatment outcome. Based on these findings, it is recommended that healthcare facilities enhance nutritional support programs, manage fever and infections promptly, and monitor weight gain during hospitalization.Item Magnitude and Determinants of Maternal Complications during Pregnancy and Post-Partum in Ethiopia: A Survey Study using PMA Data(Mekelle University, 2025-06-17) MAEDOT FISHABackground: A maternal complication is a physical or mental issue that affects the mother's health, the fetus's health, or both. Even women who were healthy before getting pregnant can experience complications. These complications may make the pregnancy a high-risk pregnancy. All pregnancies are at risk. According WHO (world health organization) most of the complications develop during pregnancy and most are preventable or treatable. Other complications may exist before pregnancy but are worsened during pregnancy. In Ethiopia the these complications were the major direct obstetric complications Objective: To determine the magnitude and determinant factors during pregnancy and postpartum complications data from PMA Ethiopia Methods: Performance Monitoring for action (PMA) surveys are a prospective cohort survey based on a multistage stratified cluster sampling design with urban-rural stratification. The sample size of this study is 1678 and the study population was women’s who have pregnant or women 0-4 weeks of postpartum. The magnitude of complications during pregnancy and postpartum period will be computed by using STATA 17 software. Multivariable logistic regression analysis was used to control confounding variables at the p-value < 0.05 and the strength of the statistical association with maternal complication during pregnancy and post partum was measured by using adjusted odds ratios and ` 95% confidence intervals. Result: magnitude of maternal complication during pregnancy and postpartum is 37.31% and38.74% respectively. Women who have develop a complication both during pregnancy and post partum were 18.3%. Women who have completed the higher education [AOR =0.191, 95% CI: (0.093, 0.392)]. A woman who has a grand multi Para [(AOR = 0.662, 95 % CI: (0.442, 0.993)]. Women’s who have obtain ANC follow up[AOR =0.758, 95% CI: (0.573, 1.004)]. Women with twin pregnancies [(AOR = 1.97, 95 % CI: (0.974, 3.963)] these factors associated with maternal complication during pregnancy. Living with a man [AOR = 2.453, 95% CI: (1.214, 4.957)]. Women who attended greater than 4 ANC follow up [AOR = 0.727, 95% CI: (0.526, 1.006)]. Women with twin pregnancy [AOR = 3.596, 95% CI: (1.225, 10.556)]. Postpartum visit [AOR = 0.682, 95% CI: (0.482, 0.965)] these factors associated with postpartum complication. Conclusion: Maternal complication during pregnancy and postpartum in Ethiopia was found to be major maternal health issue. Being living with a man, uneducated mother and their life partners, twin pregnancy, absence of post natal visit and low ANC visit were important predictors of maternal complications during pregnancy and postpartum period. By implementing targeted interventions to address the identified maternal complications, focusing on high - risk areas and populations to improve maternal health outcomes.Item DETERMINANTS OF LATE INITIATION OF ANTENATAL CARE CONTACT AMONG PREGNANT WOMEN IN HEALTH FACILITIES OF MEKELLE, TIGRAY, NORTHERN ETHIOPIA, 2024(Mekelle University, 2025-02-25) GENET TESFAMICHAELBackground: Late antenatal care is the most common issue in developing countries, including Ethiopia. In Ethiopia, 72% of pregnant women come late for their first antenatal care contact. Late antenatal care initiation is more likely to be linked to poor perinatal health outcomes. Where the effects of late antenatal care initiation are significant in Ethiopia, a scarcity of data hinders for understanding of its determinants. Objective: To identify determinants of late initiation of antenatal care contact among pregnant women in health facilities of Mekelle, Tigray, Northern Ethiopia,2024. Method: Facility based unmatched case control study was conducted in health facilities of Mekelle, Tigray, Northern Ethiopia, from 7 August -5 September, 2024. The data were collected using pre-tested structured questionnaire. In this study 592 study participants (296 cases and 296 controls) were selected using systematic random sampling technique. Cases to controls ratio was 1 to 1. Bivariate and multivariable logistic regression analysis were used to identify determinants of late antenatal care initiation and adjusted odds ratio with corresponding 95% confidence interval was used to measure strength of association. Statistical significance was declared at 𝑃-value <0.05. Result: A total of 592 study participants were included in the study with 98% response rate. Low educational level [AOR=5.60;95%CI:2.766-11.357], recognizing pregnancy by missed period [AOR=2.552; 95%CI:1.588-4.102], unplanned pregnancy [AOR=3.216; 95%CI:1.934-5.347], not accompanied by their husband to ANC contact [AOR=4.306; 95%CI:2.757-6.726] and poor knowledge of the mothers about ANC [AOR=2.049; 95%CI: 1.326-3.168] were identified as determinants of late initiation of ANC among pregnant women. Conclusion and recommendation: Low educational level, recognizing pregnancy by missed period, unplanned pregnancy, not accompanied by their husband to ANC contact and poor knowledge of the mothers about ANC were identified as determinants of late initiation of ANC among pregnant women. Therefore, Health offices and healthcare providers should focus on increasing awareness to improve women's knowledge on ANC services, and to support spouse involvement in ANC.Item WOMEN’S AUTONOMY ON MATERNAL HEALTH SERVICES UTILIZATION AND ASSOCIATED FACTORS AMONG REPRODUCTIVE AGE GROUP WOMEN IN CENTRAL TIGRAY, ETHIOPIA, 2025, A CROSS-SECTIONAL STUDY.(Mekelle University, 2025-04-21) FITHANEGES ZEREABRUKBackground: The ability of a woman to make decisions pertaining to herself and the closest members of her family are all considered aspects of women's autonomy. Many studies revealed women’s decision-making autonomy of maternal services utilization is low in many parts of the world, particularly in developing countries. The absence of previously studied research and the presence of a protracted and complex crisis in the Tigray region create a need to assess women's autonomy in maternal health service utilization and associated factors among the reproductive age group in Ethiopia. Objective: To assess women's autonomy on maternal health service utilization and associated factors among reproductive-age group women in the Central Zone, Tigray, Ethiopia, 2025. Methodology: A community-based cross-sectional study design was carried out from January to April 2025. Multi-stage sampling technique was used, and design effect was considered. The total sample size was 836, which was proportionally allocated for each randomly selected 21 kebeles of 07 woredas in the central zone of Tigray and the study participants were chosen using a systematic random sampling technique. Data were collected using Kobo Toolbox and analyzed using SPSS version 26. A pretest was done on 5% of the sample size. In the Bivariate analysis, variables with p-value < 0.25 were a candidate for the multivariable logistic regression analysis and statistical significance was declared at a p-value of <0.05. Results: Women who had autonomy in deciding whether to utilize maternal health services was 70.3% [95% CI: 67.2-73.4]. women who attend secondary education or above (AOR=18.9, 95% CI: 8.8-40.9) over no formal education, increased household annual capital by 1000 Ethiopian birrs (AOR=1.02, 95% CI: 1.01-1.03), women who get married by their choice (AOR = 6.6, 95% CI: 3.5-12.7) over their counter parts were positively associated with women’s autonomy. Conversely, increased age difference between spouses by 01 year (AOR=0.7, 95% CI: 0.6-0.8), increased women’s family size by one family member (AOR=0.4, 95% CI: 0.34-0.52) were negatively associated with women’s autonomy. Conclusion and recommendation: Women’s ability to utilize maternal health care services depends on women’s autonomy in making decisions for their health care. Accordingly, this study shows three-fourths (70.3%) of the participants were autonomous in deciding whether to use maternal health services or not. Factors significantly related to women’s autonomy in maternal health services utilization were women’s educational status, women’s annual capital, how they got married (willingness/choice), age difference between spouse, family size, and type of family. A great emphasis should be given to empowering women in terms of education, job opportunities, protecting their rights and choices during marriage, and the use of contraceptive methods to limit their family size and burden.Item MAGNITUDE AND ASSOCIATED FACTORS OF ANTISOCIAL PERSONALITY DISORDER AMONG PRISONERS AT MEKELLE CORRECTIONAL CENTER, TIGRAY, ETHIOPIA, 2024/2(Mekelle University, 2025-02-25) BRHANU MERESABackground: Antisocial personality disorder is characterized by a consistent pattern of disregard for and violating the rights of others, this condition starts in childhood or early adolescence and into adulthood. Families, relationships, and social functioning are all significantly impacted, and individuals with ASPD place a significant burden on the legal system as well as social and mental health agencies. Despite the fact that ASPD is a prevalent issue among prisoners, little research has been done on it in Ethiopia and there has not been any published research on the subject in Tigray. Objective: To assess the prevalence and associated factors of antisocial personality disorder among prisoners at Mekelle correctional center, Mekelle, Tigray, Ethiopia, 2024. Methods: A cross-sectional study was conducted at Mekelle Correctional Center with 353 participants selected through systematic random sampling. Antisocial personality disorder was assessed by the Diagnostic and Statistical Manual of Mental Disorders 5th text revision and an interviewer-administered questionnaire. Data analysis was performed using SPSS Version 27, applying bivariate and multivariable logistic regressions were done to identify factors related to antisocial personality disorder. Significant predictors of antisocial personality disorder were identified with p-values below 0.05 at a 95% confidence interval and the data ware presented using text, tables and graphs. Result: A total of 353 participants were included in the study, with a response rate of 98.33%. The prevalence of antisocial personality disorder among prisoners was found to be 23.8%, with a 95% CI of (19.4, 28.6). This study found statistically significant associations between antisocial personality disorder and history of mental illness (AOR = 2.79, 95% CI: 1.15, 6.81), previous incarceration (AOR = 3.30, 95% CI: 1.33, 8.22), poor social support (AOR = 3.72, 95% CI: 1.63, 8.49), and adverse childhood experiences (AOR = 4.68, 95% CI: 1.38, 15.80). Conclusion: According to this study about one-quarter of the participants were found to have an anti-social personality disorder antisocial personality disorder among prisoners. History of mental illness, previous incarceration, poor social support, and adverse childhood experiences(s) were factors statistically associated with antisocial personality disorder. Addressing these factors could help reduce antisocial personality disorder prevalence and improve the mental health of the incarcerated population.Item DETERMINANTS OF INCOMPLETE VACCINATION AMONG CHILDREN AGED 12-23 MONTHS IN NAEDIER WOREDA, CENTRAL ZONE, TIGRAY, ETHIOPIA, 2024/2025 COMMUNITY BASED UNMATCHED CASE CONTROL STUDY(Mekelle University, 2025-02-21) GEBERZIHER GEBERSLASSIEBackground: Vaccination is among the most cost-effective health interventions and has been responsible for substantial reductions in mortality and morbidity, especially for those under five. Globally, around 67 million children are only partially immunized. Neglecting to protect children from vaccination can lead to severe outcomes such as permanent disability, child mortality, and vaccine-preventable disease outbreaks. In Africa, an estimated 12.7 million children, 1.4 million children in Ethiopia and 41% of children in Tigray are partially immunized. The reasons behind these incomplete vaccinations haven't been extensively studied. Therefore, this study aimed to identify the determinants of incomplete vaccination among children aged 12-23 months in Naedier Woreda, Central Zone, Tigray, Ethiopia, 2024 /2025 Methods: A community-based unmatched case-control study design was implemented with a total sample size of 294 among children aged 12 to 23 months in Naedier Woreda, Central Zone of Tigray, Ethiopia, from August to October 2024. A participant was selected from 12 Kebeles by a simple random sampling technique. Data was collected from mothers/caregivers using a pretested, structured questionnaire. Data were entered into Epi Info 7 and analyzed using the Statistical Package for Social Sciences version 27. Multicollinearity was checked using the variance inflation factor, and the model of fitness was checked by Hosmer Lemeshow. Multivariable logistic regression analysis was used to control confounding variables at the p-value < 0.05, and the strength of the statistical association was measured by using adjusted odds ratios and ` 95% confidence intervals. Result: This study revealed that children born to mothers/caregivers who did not receive antenatal care follow-up (AOR = 4.58, 95% CI: 1.23-17.1), households not visited by health workers (AOR = 2.53, 95% CI: 1.23-5.17), mothers/caregivers who were not informed about the types of vaccines received (AOR = 3.209, 95% CI: 1.29-8.0), were not informed about potential side effects of vaccines (AOR = 2.92, 95% CI: 1.36-6.31), and were not given information about the next vaccination date (AOR = 3.76, 95% CI: 1.8-7.42) were the determinants to default on completing their vaccination. Conclusions and Recommendations: From this study, suggested several determinants contributing to children aged 12-23 months failing to complete their full vaccination schedule are no antenatal care follow-up, absence of home visits by healthcare workers, and no information on vaccinations, including potential side effects and subsequent vaccination schedules. To address those factors, health offices and healthcare workers should prioritize providing detailed information about the specific vaccines administered, including expected side effects and the timing of future vaccinations, and reinforce the importance of consistent antenatal care for both maternal and child health.