College of Health Sciences
Permanent URI for this communityhttps://repository.mu.edu.et/handle/123456789/67
Browse
11 results
Search Results
Item Magnitude and Associated Factors of Oligohydramnios Among Third Trimester Pregnant Women Attending at Mekelle Public Hospitals, Tigray, Ethiopia: Institution-Based Cross Sectional Study(Mekelle University, 2025-06-28) SHUSHAY TEKULUBackground: Oligohydramnios is a condition where amniotic fluid volume is lower than expected for gestational age. It is the most common amniotic fluid disorder and the leading cause of severe fetal and maternal adverse outcomes. Despite the severity of the problem, studies regarding the magnitude and associated factors of oligohydramnios in third-trimester pregnancy were limited in Ethiopia, mainly in the study area. Objective: To assess magnitude and associated factors of oligohydramnios among women in the third trimester of pregnancy at Mekelle public hospitals, Tigray, Ethiopia, 2024/2025. Methods: A cross-sectional study was conducted from December/1/2024 to May/30/2025 in Mekelle city. We included pregnant women using consecutive sampling technique using predefined inclusion criteria. Interview using structured questionnaire was employed to collect socioeconomic and demographic, lifestyle, medical and obstetric related data. The data were analyzed using SPSS version 27. Descriptive statistics were utilized to summarize data. Binary logistic regression analysis was employed to identify factors associated with oligohydramnios in third-trimester of pregnancy. Variables with P<0.05 in multi-variable analysis were declared statistically significant & interpreted using AOR with 95% CI. Hosmer-Lemeshow test was used to assess model fitness & it was insignificant (P=0.956), indicating a good-fitted model for the data. The maximum VIF was 1.12, telling that no Multicolinearity issue among covariates. Results: The mean age of the study participant, 356 with a 100% response rate, was a 28.2±5.06 years. The magnitude of oligohydramnios in third trimester of pregnancy was 7.9% (95% CI: 5.3-11.2%). Women with a history of diabetes mellitus [AOR=4.12 (95% CI: 1.26-13.53)], hypertension [AOR=6.12 (95% CI: 1.82-20.59)], anemia [AOR=4.63 (95% CI: 1.61-13.37)], hyperemesis gravid arum [AOR=4.76 (95% CI: 1.82-12.48)], post-term pregnancy [AOR=7.22 (95% CI: 1.41-36.98)] and fetal factors, including congenital anomalies [AOR=7.60 (95% CI: 1.81-31.94)] and intrauterine growth restriction [AOR=5.87 (95% CI: 1.42-24.32)], were significantly associated with an increased odds of oligohydramnios. Conclusion & Recommendations: 7.9% of pregnant women had sustained oligohydramnios. Maternal diabetes, hypertension, anemia, hyperemesis gravid arum, post-term pregnancy, fetal congenital anomalies and intrauterine growth restriction were identified as significant risk factors for oligohydramnios. We recommend increased surveillance for oligohydramnios focusing on the identified risks, maternal life style modifications & regular antenatal checkups in pregnancy.Item Sero-prevalence of hepatitis B virus and human immunodeficiency virus, and associated factors among pregnant women attending antenatal care in selected general hospitals of Mekelle and Eastern zone of Tigray region, Northern Ethiopia(Mekelle University, 2025-06-28) SENAIT KEBEDEBackground: Hepatitis B virus (HBV) and Human Immunodeficiency Virus (HIV) share common transmission risk factors and represent significant global public health challenges. They are major contributors to morbidity and mortality among pregnant women, especially in low and middle-income countries. However, there is limited local data on the burden of these infections among pregnant women in the study area collectively. Hence, this study was aimed to assess the sero-prevalence of hepatitis B viruses (HBV) and human immunodeficiency viruses (HIV), and associated factors among pregnant women attending antenatal care in selected general hospitals of Mekelle and Eastern Zone of Tigray, Northern Ethiopia. Method: A hospital based cross sectional study was conducted from December 2024 to April 2025 in selected general hospitals of Mekelle and Eastern zones of Tigray. Socio-demographic risk factors data and blood sample were collected from the 238 pregnant women. Rapid diagnostic tests were used to detect HBV and HIV. HBV confirmation with Enzyme linked immune sorbent assay (ELISA) was also performed. Data was entered and analyzed using SPSS version 27. Descriptive and Logistic regression analysis was used to assess associations between variables. A p-value of ≤0.05 was considered as statistical significant. Result: The overall seroprevalence of HBV and HIV were 9.7% and 4.2% respectively. However, no cases of HBV/HIV co-infection were identified. Among the three sites the seroprevalence of HBV and HIV were 8.9% & 3.7%, 8% & 2.7% and 11.9% & 6% in Adigrat, Wukro and Mekelle respectively. Variables like older age (AOR = 3.10, 95% CI: 1.01–9.46, P = 0.047), history of liver disease (AOR = 23.67, 95% CI: 3.55–158.01, P = 0.001), history of abortion (AOR: 0.23, 95% CI: 0.05-0.96; p=0.043), nose piercing (AOR: 4.01, 95% CI: 1.35, 11.92; p=0.013) and history of sexually transmitted infection(AOR: 5.94, 95% CI: 1.41-24.99; p=0.015) were revealed significant association with seroprevalence of HBV while knowledge about transmission of HIV (Exact OR = 0.10, 95% CI: 0.02–0.72, p = 0.0219) was the only variable significantly associated with of HIV infection. Conclusion: The overall seroprevalence of HBV among pregnant women attending antenatal care was high according to WHO classification. The current HIV prevalence lies within the range of the pooled HIV prevalence among pregnant women in EthiopiaItem Bacterial Urinary Tract Infections, Antimicrobial Susceptibility Patterns and Associated Risk factors Among Fistula patients at Hamlin Fistula Hospital, Mekelle, Tigray, North of Ethiopia(Mekelle University, 2025-06-28) KASECH FITSUM TEDLABackground: Urinary tract infections (UTIs) are one of the most common bacterial infections in humans, both in the community and hospital. UTIs are a significant cause of hospital admissions, a widespread concern, affecting millions of people worldwide and causing significant morbidity, mortality, and serious healthcare costs. Patients with obstetric fistula usually suffer from urinary and stool incontinence that can predispose them to frequent infections with urinary tract infection. Despite this fact, there is lack of data on the prevalence, causative pathogens, and antimicrobial susceptibility patterns of UTIs, particularly in lower resource settings like Tigray, Ethiopia. Objective: The study aimed to assess the prevalence of bacterial urinary tract infection, evaluate antimicrobial susceptibility patterns and identify associated risk factors among fistula patients at Hamlin Fistula Hospital in Mekelle, Tigray, Ethiopia. Method: A cross-sectional study was conducted from January to May 2025 at Hamlin Fistula Hospital in Mekelle, Tigray. Socio-demographic characteristics and other urinary tract infection related risk factors were collected from study participants using structured questionnaires. The mid-stream urine was collected and cultured on Cysteine lactose electrolyte deficient agar, and MacConkey agar. Bacterial isolates of gram negative and gram positive were characterized using series of biochemical tests. Antimicrobial susceptibility was determined using the disc diffusion method and interpreted according to the Clinical and Laboratory Standards Institute (CLSI2020) guidelines. The data was entered and analyzed using SPSS version 27. Results: Out of the 151 patients sampled, 104 (68.8.6%) were found to have significant bacteria infecting the urinary tract. Isolation of significant bacteriuria was strongly associated with the history of previous UTI and history of catheterization (p=0.01). Eight different species of bacterial uropathogens were identified from the samples. The bacteria isolated were 94.2 % gram negative and 5.8% gram positive. The most predominant bacteria identified were E. coli followed by P.vulgaris. The isolated bacteria had shown the highest resistance rate (72.2%) to Tetracyllin followed by Ampicillin (69.2%) and highest susceptibility to Amikacin (100%) followed by Meropenem (98.1%). Twenty-six of the isolated bacteria (98) were found to be ESBL-producing gram-negative bacteria. Conclusion and recommendation: The overall prevalence of urinary tract infection among fistula patients is high. The predominant pathogen of UTI isolated was E. coli followed by P.vulgaris and K. peumoniae. All the bacterial isolates have shown multiple antibiotic resistance pattern. Based on the findings of the present study, routine screening, urine culture and antimicrobial susceptibility testing are recommended for all fistula patients.Item Predictors of clinical severity , immunological failure and magnitude of intestinal parasitic infections among HIV Patients on ART in Mekelle General Hospital, Tigray, Ethiopia.(Mekelle University, 2025-06-28) GIRMAY ALEMSEGEDBackground: Untreated intestinal parasitic co-infections appeared to hasten the progression of HIV-1 disease. However, there had been few studies to ascertain the interference and their induced severity of intestinal parasitic infections among on ART HIV/AIDS patients in resource-limited settings such as Ethiopia, where HIV/AIDS management largely depended on CD4+ T cells counts, viral load, and WHO clinical staging. Objective: To assess predictors of clinical severity, immunological failure and magnitude of intestinal parasitic infections in HIV Patients on ART in Mekelle General Hospital, Tigray, Ethiopia. Methods: A health facility based cross-sectional study was carried out from December 2024 to March 2025 among adult HIV/AIDS patients on ART. Data on socio-demographic, clinical and risk factors were gathered using a pre-tested structured questionnaire. Intestinal parasite were detected using direct microscopic examination, the formal ether concentration methods, and the Modified Ziehl–Neelsen technique, CD4 cell quantification was performed using the BD FACS Count System, while viral load measurement was conducted with the 2000rt Abbott machine. Multivariable logistic regression analysis determined the association between predictors and outcomes. P-value ≤ 0.05 was considered statistically significant. Results: The prevalence of intestinal parasites among HIV/AIDS patients was found to be 31.5% (100/318), of these 92.0 % (92/100) protozoans and 8.0% (8/100) helminthes. Among the identified parasites, Entamoeba histolytica/dispar had the highest prevalence 13.8% (44/318), followed by Giardia lamblia 10.4% (33/318) and Isospora belli was detected in 3.5% (11/318). The overall magnitude of clinical severity and immunological failure were 33.3% (106/318) among on ART patients, of these 26.7% (85/318) clinical severity and 29.3% (93/318) immunological failure. Among these, 72.3% (64 /85) had disclosed their HIV status, while 69.4% (59/85) demonstrated fair or poor adherence to antiretroviral therapy (ART). The prevalence of clinical and immunological failure among patients with parasitic infections was 53% (53/100). Significant association was observed between parasite infection and CD4+ T cell counts below 200/µl (AOR: 3.4, 95% CI: 1.5-8.5, p=0.005) as well as viral load levels equal to or greater than 1000 copies/ml (AOR: 3.2, 95% CI: 1.7-5.9, p=0.000). Several factors were associated with an increased likelihood of clinical severity and immunological failure, including smoking habits, occupational status, low BMI and an ambulatory or bedridden functional status at the last ART visit. Conclusions: The prevalence of intestinal parasites was higher among HIV patients on ART of these, E. histolytica, G.lambelia and Isospora belli were the leading causes of clinical severity and immunological failure on those individuals who were their CD4 count less than 200 cells/mm3, viral load greater than 1000 copies/µl. The overall severity of clinical conditions and immunological failure was significantly high among patients on ART who had smoking habits, occupational status, low body mass index, and an ambulatory or bedridden functional status.Item FERTILITY DESIRE AND ITS ASSOCIATED FACTORS AMONG WOMEN ATTENDING ANTIRETROVIRAL THERAPY AT PUBLIC HOSPITALS IN MEKELLE, TIGRAY, ETHIOPIA, 2024: CROSS SECTIONAL STUDY(Mekelle University, 2025-02-25) SOLOMON TEKLUBackground: Fertility desire is defined as having motivation or intention to give birth by individuals in their future life irrespective the number of children. Fertility desire has undesirable effect on the transmission of human immunodeficiency virus to the partner due to unsafe sex, vertical transmission to the children and there will be also disagreement with the strategies developed for elimination of human immunodeficiency virus/acquired immunodeficiency syndrome in countries including Ethiopia. Objective: To assess the prevalence of fertility desire and its associated factors among women attending antiretroviral therapy at public hospitals in Mekelle, Tigray, Ethiopia, 2024. Methods and Materials: Institutional based cross-sectional study was conducted among 355 women and participants were selected using systematic random sampling method. The data were collected from August 1, 2024 to August 30, 2024 using pre-tested and interviewer administer questionnaire. Few variables were recorded from participant’s card. The data were analyzed using statistical package for social science version 27. Binary logistic regression method of analysis was used. All variables with P-value <0.25 in bivariate were included in the multivariable binary logistic regression analysis. The strength of the association was interpreted using an adjusted odds ratio with its 95% confidence interval. Statistically significant variable was declared at P-value < 0.05. Finally, the data were presented with texts, tables, figures, and graphs. Results: This study included 355 women, of them 345(97.2%) responded to the study. The prevalence of fertility desire was 182(52.8%, 95% CI: 46.6%-59.1%). Being single 69.3% (AOR: 0.307, 95% CI: O.111-0.84), being widowed 91% (AOR: 0.09, 95% CI: 0.038-0.214), being divorced 76.7% (AOR: 0.233, 95% CI: 0.109-0.497), number of women’s child 50.8% (AOR: 0.492, 95% CI: 0.382-0.632) and knowledge of women on prevention mother to child transmission 24.5% (AOR: 0.755, 95% CI: 0.608-0.938) were negatively associated with fertility desire. Conclusion and recommendation: This study revealed that more than half of participants had fertility desire and factors associated with it were marital status, number of women’s child, knowledge of the women on prevention mother to child transmission. All stakeholders should take into account the prevalence of fertility and its associated factors while serving the women living with human immunodeficiency virus and counsel the women to decrease their interest on the number of children and promote knowledge on the prevention of mother to child transmission.Item MAGNITUDE AND ASSOCIATED FACTORS OF TB/HIV CO INFECTION AMONG HIV INFECTED PATIENTS ATTENDING IN MEKELLE PUBLIC HOSPITALS, TIGRAY, ETHIOPIA 2024/25(Mekelle University, 2025-05-21) KAHSU TSEGAYIntroduction: -Tuberculosis is a contagious air born disease caused by Mycobacterium tuberculosis species and the leading causes of morbidity and mortality among people living with HIV/AIDS worldwide accounting for about 25% of all causes of the deaths. HIV infected clients are more susceptible to Tuberculosis infection. The World Health Organization Global Tuberculosis report of 2018 estimated that 10.0 million new cases of Tuberculosis occurred in 2017, of which over 82% of Tuberculosis deaths occurred in low- and middle-income countries. Evidence from this study helps to develop policies that address TB and HIV in an integrated, cost-effective manner and more efficient use of funds and resources. Objective: - The aim of this study was to assess the Magnitude and its associated factors of TB/ HIV co-infection among HIV infected patients in public hospitals of Mekelle, Tigray, Ethiopia 2025. Methods and materials: - Institutional based cross-sectional study was conducted and the period of data collection was from November to December 2024 G.C among ART patients. Systematic sampling technique was used to select 394 participants from the total source population. Data were collected using a pretested, interviewer, administered questionnaire and reviewing the medical record of the patient (CD4 cell count, hemoglobin level, BMI, WHO clinical stage, diagnosis of opportunistic infections, and TB). Data collection tool was pretested in 5% of total sample size in Wukro General Hospital. Data were coded and entered in to Epi data and was exported to statistical package for social science version 27 for statistical analysis. Descriptive statistics were performed. Both bivariate and multivariable logistic regression analyses were used to determine the association between independent variable and dependent variable. Variables having p value less than 0.25 in the bivariate analysis were exported in to multivariate logistic regression in multivariate logistic regression, p value <0.05 with 95% confidence interval (CI) was considered statistically significant. The Hosmer- Lemeshow goodness-of-fit model coefficients tests procedure was used to test for model fitting. Result – The magnitude of TB/ HIV co-infection was 18.8% and confidence interval (18.761 – 18.839). Marital status being widowed (AOR and 95% CI 0.238 (0.062, 0.903), hemoglobin level less than 11 (AOR and 95% CI 4.937 (1.884, 12.943), low CD4 count (200 cells mm3) (AOR and 95% CI 3.405 (1.174, 9.872), suspected TB patients in the household AOR and 95% CI 2.59 (1.026, 6.562) opportunistic infection without TB AOR and 95% CI (6.169 (2.272, 16.747), ambulatory AOR and 95% CI 22.906 (4.918,106.697), Bedridden AOR and 95% CI 11.436 (3.461, 37.79), poor drug adherence AOR and 95% CI 3.767 (1.389, 10.221), alcohol consumption AOR and 95% CI 15.129 (5.232, 43.748), raw/un cook foods consumption AOR and 95% CI 3.255 1.094, 9.682. were significant determinants of TB/HIV co-infection among HIV clients. Conclusion and recommendation The prevalence of tuberculosis among ART patients was high and this study indicated that marital status, hemoglobin level, CD4 count, presence of suspected TB patients in the household, presence of opportunistic infection without TB, functional status, drug adherence, alcohol consumption, utilization of raw/un cook foods were found significantly associated with TB/HIV co-infection. Providing counseling and health education regarding drug adherence, alcohol consumption and chat chewing to ART patients, and government should give priority on TB/ HIV confection.Item DETERMINANTS OF LATE INITIATION OF ANTENATAL CARE CONTACT AMONG PREGNANT WOMEN IN HEALTH FACILITIES OF MEKELLE, TIGRAY, NORTHERN ETHIOPIA, 2024(Mekelle University, 2025-02-25) GENET TESFAMICHAELBackground: Late antenatal care is the most common issue in developing countries, including Ethiopia. In Ethiopia, 72% of pregnant women come late for their first antenatal care contact. Late antenatal care initiation is more likely to be linked to poor perinatal health outcomes. Where the effects of late antenatal care initiation are significant in Ethiopia, a scarcity of data hinders for understanding of its determinants. Objective: To identify determinants of late initiation of antenatal care contact among pregnant women in health facilities of Mekelle, Tigray, Northern Ethiopia,2024. Method: Facility based unmatched case control study was conducted in health facilities of Mekelle, Tigray, Northern Ethiopia, from 7 August -5 September, 2024. The data were collected using pre-tested structured questionnaire. In this study 592 study participants (296 cases and 296 controls) were selected using systematic random sampling technique. Cases to controls ratio was 1 to 1. Bivariate and multivariable logistic regression analysis were used to identify determinants of late antenatal care initiation and adjusted odds ratio with corresponding 95% confidence interval was used to measure strength of association. Statistical significance was declared at 𝑃-value <0.05. Result: A total of 592 study participants were included in the study with 98% response rate. Low educational level [AOR=5.60;95%CI:2.766-11.357], recognizing pregnancy by missed period [AOR=2.552; 95%CI:1.588-4.102], unplanned pregnancy [AOR=3.216; 95%CI:1.934-5.347], not accompanied by their husband to ANC contact [AOR=4.306; 95%CI:2.757-6.726] and poor knowledge of the mothers about ANC [AOR=2.049; 95%CI: 1.326-3.168] were identified as determinants of late initiation of ANC among pregnant women. Conclusion and recommendation: Low educational level, recognizing pregnancy by missed period, unplanned pregnancy, not accompanied by their husband to ANC contact and poor knowledge of the mothers about ANC were identified as determinants of late initiation of ANC among pregnant women. Therefore, Health offices and healthcare providers should focus on increasing awareness to improve women's knowledge on ANC services, and to support spouse involvement in ANC.Item MAGNITUDE AND ASSOCIATED FACTORS OF ANTISOCIAL PERSONALITY DISORDER AMONG PRISONERS AT MEKELLE CORRECTIONAL CENTER, TIGRAY, ETHIOPIA, 2024/2(Mekelle University, 2025-02-25) BRHANU MERESABackground: Antisocial personality disorder is characterized by a consistent pattern of disregard for and violating the rights of others, this condition starts in childhood or early adolescence and into adulthood. Families, relationships, and social functioning are all significantly impacted, and individuals with ASPD place a significant burden on the legal system as well as social and mental health agencies. Despite the fact that ASPD is a prevalent issue among prisoners, little research has been done on it in Ethiopia and there has not been any published research on the subject in Tigray. Objective: To assess the prevalence and associated factors of antisocial personality disorder among prisoners at Mekelle correctional center, Mekelle, Tigray, Ethiopia, 2024. Methods: A cross-sectional study was conducted at Mekelle Correctional Center with 353 participants selected through systematic random sampling. Antisocial personality disorder was assessed by the Diagnostic and Statistical Manual of Mental Disorders 5th text revision and an interviewer-administered questionnaire. Data analysis was performed using SPSS Version 27, applying bivariate and multivariable logistic regressions were done to identify factors related to antisocial personality disorder. Significant predictors of antisocial personality disorder were identified with p-values below 0.05 at a 95% confidence interval and the data ware presented using text, tables and graphs. Result: A total of 353 participants were included in the study, with a response rate of 98.33%. The prevalence of antisocial personality disorder among prisoners was found to be 23.8%, with a 95% CI of (19.4, 28.6). This study found statistically significant associations between antisocial personality disorder and history of mental illness (AOR = 2.79, 95% CI: 1.15, 6.81), previous incarceration (AOR = 3.30, 95% CI: 1.33, 8.22), poor social support (AOR = 3.72, 95% CI: 1.63, 8.49), and adverse childhood experiences (AOR = 4.68, 95% CI: 1.38, 15.80). Conclusion: According to this study about one-quarter of the participants were found to have an anti-social personality disorder antisocial personality disorder among prisoners. History of mental illness, previous incarceration, poor social support, and adverse childhood experiences(s) were factors statistically associated with antisocial personality disorder. Addressing these factors could help reduce antisocial personality disorder prevalence and improve the mental health of the incarcerated population.Item UNINTENDED PREGNANCY AND ASSOCIATED FACTORS AMONG PREGNANT WOMEN ATTENDING ANTENATAL CARE IN MEKELLE CITY PUBLIC HEALTH FACILITIES, TIGRAY REGION, ETHIOPIA, 2025(Mekelle University, 2025-04-28) TSEGA WELEGEBRIALUnintended pregnancy is an important public health problem for women of child - bearing age, because of its negative impacts on health and social for both mothers and children. Unintended pregnancy causes maternal mortality and morbidity. Worldwide, although unplanned pregnancies seem to be decreasing, 38% of pregnancies are unintended. In sub-Saharan Africa, unintended pregnancy accounts for more than a quarter of the 40 million pregnancies that occur annually. In Ethiopia, about 17% and 8% of pregnancies are mistimed and unwanted, respectively. But, there is lack of information particularity post-conflict recovery in the study area on the prevalence of unintended pregnancy and its associated factors. To assess the prevalence and associated factors of unintended pregnancy among pregnant women attending antenatal care in Mekelle City Public Health Facility, Tigray region, Ethiopia, 2025. A facility-based cross-sectional study was conducted among 394 Pregnant women attending ANC in Mekelle City Public Health Facility. A simple random sampling technique was used to select study health facilities and a systematic random sampling technique was used to select study participants. Data was collected via face-to-face interview using a structured questionnaire. Data were entered into SPSS version 25 for analysis. Descriptive, bivariate, and multivariate logistic regression analyzes were used to identify the association. Variables that showed a P-value of less than 0.25 during the bivariate analysis were used and were entered into a multivariate logistic regression model to identify their independent effects. Odds ratio with a 95% CI & p value of less than 0.05 were computed to assess the presence and degree of statistical association between dependent and independent variables. The overall magnitude of unintended pregnancy was 32.7% with 95% CI (27.9, 38.1). Of those, 89.1% were mistimed and 10.9% were unwanted. The multiple logistic regression results revealed that, age group from 15 to 24 (AOR=4.702,95% CI 1.948,11.348). The women and husband’s decision in the family planning (AOR=0.292,95% CI 0.155,0.551), family size of 3-5(AOR=2.730,95%CI 1.512,4.930) and family size of≥6(AOR=3.967,95%CI 1.228,12.817), no formal education (AOR=3.336, 95%CI 1.340,8.308) were significantly associated with unintended pregnancy. There is no single factor accounted for the relatively high of unintended pregnancy rather many factors were interwoven to affect the event. Efforts should be made to scale up shared decision-making power in family planning services and there is the need to promote family planning services and awareness to minimize unintended pregnancy.Item Assessment of Schistosoma mansoni Infection and Associated Risk Factors Among Elementary School Children in Gembella and Feleg-Daero, Mekelle City, Ethiopia(Mekelle University, 2025-04-25) Abeba TekluSchistosomiasis is a widespread parasitic infection transmitted through contact with contaminated water, posing a major global public health challenge, particularly in developing countries. It affects individuals of all ages, with children being among the most vulnerable. Identifying the prevalence, associated risk factors, and high-risk populations is crucial for designing and implementing effective prevention and control strategies. This study aimed to assess Schistosoma mansoni infection and the associated risk factors among elementary school children in Gembella and Feleg-Daero (Adis Alem) elementary schools, in Mekelle City, Ethiopia. A cross-sectional study was conducted from January to September 2024, employing a purposive sampling technique to select schoolchildren. A total of 308 stool samples collected from elementary school children aged 7 to 20 years were examined using the wet mount and Kato-Katz techniques. A pre-tested questionnaire was utilized to gather socio-demographic information and associated risk factors. The data was coded, entered, and analyzed using descriptive statistics, bivariate and multivariate logistic regression and the significance level was set at p < 0.05 with 95% confidence interval. The overall prevalence of Schistosoma mansoni infection was 51.0% (157/308), with a median infection intensity of 192 eggs per gram of stool (EPG) among infected individuals. Among the infected children, 26.1%, 49.7% and 24.2% had light, moderate and heavy infections respectively. Significant risk factors for Schistosoma mansoni infection included swimming (AOR: 4.89; 95% CI:1.35, 17.75, P<0.001), washing clothes in rivers or streams (AOR:3.72; 95% CI: 1.12,12.37, P<0.001), engaging in irrigation activities (AOR:1.03;95%CI: 0.28,3.77, P<0.022), and bathing in river (AOR: 2.19,95% CI, 0.17-28.76, P< 0.001) and water contacts with flowing river (AOR:1.41; 95%CI: 0.23, 8.50, P<0.001). Schistosoma mansoni infection among children in this study was alarmingly high, with nearly half of the infected cases classified as having moderate intensity. These findings underscore the urgent need for targeted interventions, including health education, improved access to safe water, and regular deworming programs, to effectively reduce the disease burden and its associated risks.