College of Health Sciences

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    COVID-19 VACCINE UPTAKE AND ASSOCIATED FACTORS AMONG PREGNANT WOMEN OF MEKELLE CITY, TIGRAY, ETHIOPIA: A MIXED STUDY DESIGN
    (Mekelle University, 2025-02-21) MEKONEN G/MESKEL
    Background: Adhering to the prevention practices for COVID-19 is paramount than treating the patients. The World Health Organization recommends different prevention and control measures for COVID-19. This study set out to assess COVID-19 vaccine uptake and associated factors among pregnant women in Tigray. Objective: To assess COVID-19 vaccine uptake andassociated factors among pregnant women attending antenatal care in selected public health facilities of Mekelle, Tigray, Ethiopia 2024. Methodology: An institutional-based cross-sectional study design supplemented by a qualitative method was conducted among 228 pregnant women from December to February 2025. A systematic random sampling technique was used to select study participants for the quantitative study, and purposive sampling was used for the qualitative part. Data were collected by trained nurses and midwives using a structured questionnaire. The quantitative data were analyzed using IBM SPSS 27. The qualitative data were analyzed using thematic analysis. A binary logistic regression model was used to assess the association between the dependent and independent variables. Statistical significance was declared at a P value of < 0.05. Result: The mean age of the respondents was 30.3 years, and 54.2% of them were multigravida. Good knowledge and positive attitude about the COVID-19 vaccine were found in 57.5% and 58.9% of the women, respectively. The magnitude of COVID-19 vaccine uptake was 14.5%, and all who took the vaccine reside in urban areas. The odds of uptake were about 6 times higher among pregnant women who attended formal education up to college/university (AOR=5.7, 95% CI: 1.6 to 21.2). The odds of uptake were 4-fold higher among pregnant women who had a history of contact with a confirmed COVID-19 case (AOR=4.1, 95% CI: 1.3 to 13.0). The odds of uptake were 3.6 times higher among pregnant women who had a positive attitude towards the COVID-19 vaccine (AOR=3.6, 95% CI: 1.3 to 9.8). Conclusion and recommendation: This study found that COVID-19 vaccine uptake among pregnant women in Mekelle was low. Hence, health education and discussion about the benefits and safety of COVID-19 vaccination, ensuring that COVID-19 vaccines are readily available and accessible, and conducting outreach COVID-19 vaccination programs can improve uptake of COVID-19 vaccine among pregnant women.