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    PREVALENCE AND ASSOCIATED RISK FACTORS OF PLUMONARY TUBERCULOSIS AMONG PRISONERS IN SHIRE, AXUM AND ADWA PRISON CENTRS
    (Mekelle University, 2025-06-28) GIRMASLASIE FISEHA
    Background: Pulmonary Tuberculosis is a contagious airborne disease caused by Mycobacterium tuberculosis and remains a significant global public health problem. Prisons, due to overcrowding, poor ventilation, and limited healthcare services, present a high-risk environment for TB transmission and progression. In the Tigray region of Ethiopia, challenges such as inadequate diagnostic capacity and insufficient data hinder effective TB control among incarcerated populations. Objective: This study was aimed to determine the prevalence of pulmonary tuberculosis and identify its associated risk factors among prisoners in Shire, Axum, and Adwa correctional facilities in Tigray, Ethiopia, over the period from December, 2024 to May, 2025. Methodology: An institutional-based cross-sectional design was employed to enroll 265 prisoners presenting with TB symptoms. Structured questionnaires were collected socio-demographic and clinical information, including HIV status, history of smoking, and incarceration-related exposures. Sputum samples were collected and analyzed using Ziehl-Neelsen staining and the Gen-expert MTB/RIF assay. Results: A total of 265 prisoners were enrolled in this study, drawn from a total incarcerated population of 3,180 inmates across the three prison centers in Shire, Axum, and Adwa, located in northern Ethiopia. The study identified 5 bacteriologically confirmed TB cases, yielding a point prevalence of 1.9% (95% CI: 0.6%–4.3%) among the study participants. Occupation prior to imprisonment was significantly related to TB status: prisoners who had been governmentemployed or self-employed had significantly lower odds of TB infection compared to those who had been daily laborers or unemployed (exact AOR = 0.119, 95% CI: 0.000–0.946, p = 0.0432). Prisoners who were HIV-negative or whose HIV status was unknown had significantly lower odds of TB compared to HIV-positive individuals (exact AOR = 0.033, 95% CI: 0.001–0.722, p = 0.0281). Conclusions and Recommendations: The prevalence of PTB was high in these prison centers. There should be an intensified implementation of TB screening among high-risk inmates, particularly those with a history of unemployment, HIV infection, smoking, or TB symptoms.
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    PREVALENCE AND FACTORS ASSOCIATED WITH FAILD INDUCTION OF LABOR AMONG WOMEN UNDERGOING INDUCTION AT PUBLIC HOSPITALS OF MEKELLE CITY, TIGRAY
    (Mekelle University, 2025-06-28) HABEN NIGUSE
    Introduction: Induction of labor is more frequently used obstetric procedure, practiced in over 20% of pregnancies globally, with 20% resulting in cesarean delivery. Worldwide, unsuccessful induction of labor is a public health concern. Numerous unfavorable outcomes for both the mother and fetus are linked to it, including postpartum hemorrhage, uterine rupture, birth asphyxia, and prolonged hospital stays. This study aimed to assess the prevalence and factors associated with failed induction of labor among women undergoing induction at public hospitals of Mekelle city, Tigray origin, Ethiopia. Objective: To determine the prevalence and factors associated with failed induction of labor among women undergoing induction at public hospitals of Mekelle city, Tigray, 2024/25 Method: A facility-based cross-sectional study design was implemented on 312 samples from women undergoing labor induction at public hospitals of Mekelle city from September to October, 2024. The sample size was allocated to the selected hospitals proportionally. A structured questionnaire was used for interview of woman on induction and checklist was used to extract data from medical records. Data was analyzed using Statistical Package for Social Science version 27. Binary logistic regression model was used to see the association between dependent and independent variables and multivariable logistic regression was used to identify the independent predictors of failed labor induction. Odds ratio with 95% confidence interval computed and level of significance declared at P-value <0.05. Result: This study showed that the prevalence of failed induction was 26.3% (95% CI: 21.6- 31.4). Factors associated with failed inductions were; Lack of labor induction history (AOR: 10.6; 95% CI: 1.61-70.29), no artificial rupture of membrane (AOR: 4.1; 95% CI: 1.28–13.27), shorter maternal height, (AOR=0.9, 95% CI: 0.88–0.99), and longer induction-to-delivery time (AOR= 0.9, 95% CI: 0.80–0.98). Conclusion: The prevalence of failed induction was high in this study. Lack of labor induction history, no artificial rupture of membrane, shorter maternal height, and longer induction-todelivery time were independent predictors for failed induction of labor. Recognizing these factors and timely interventions can help reduce the risk of failed inductions and improve both maternal and neonatal outcomes.
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    Magnitude and Associated Factors of Anemia Among First Trimester Pregnant Women Attending Antenatal Care at Public Hospitals in Mekelle city, Tigray, Ethiopia, 2025: A Cross-sectional Study
    (Mekelle University, 2025-06-28) Abrahaley Hadush
    Background: Detecting anemia and identifying its risk factors in the first trimester pregnant women is very crucial to prevent and treat it early. Despite this, data regarding anemia among women in such early pregnancy is quite limited in Ethiopia and particularly in Tigray. Therefore, this study aimed to determine the magnitude and factors associated with anemia among first trimester pregnant women attending antenatal care follow up at public hospitals in Mekelle city, Tigray, Ethiopia. Methods: A hospital-based cross-sectional study was conducted from January to February 2025 at public hospitals in Mekelle city. The sample size was 396 and consecutive sampling was used to recruit them. Interviews using structured questionnaires were employed to collect sociodemographic, nutritional and maternity related data. Laboratory measurements were performed to determine the level of hematological parameters. The data were exported, cleaned, coded and analyzed using SPSS Version 27.0. Descriptive statistics were utilized to summarize the data collected. Logistic regression analysis was used to identify factors associated with anemia in the first trimester of pregnancy. P-value < 0.05 was used to declare statistical significance. Result: A total of 396 respondents were included in this study and their mean age was 28.5 ± 5.80 years. The magnitude of anemia among the first trimester pregnant women was 13.4% (95% CI; 10.2-17.1). Out of them, 38 (71.7%) were mildly anemic while 13 (24.5%) and 2(3.8%) were moderately and severely anemic respectively. The mean hemoglobin level was 12.33(± 1.48) g/dl. Low dietary diversity (AOR=4.36, 95% CI: 1.74, 1..87); feeding frequency (AOR=2.43, 95% CI: 1.03, 5.72); coffee/tea consumption (AOR = 2.81, 95% C:1.22, 6.48); low mid-upper arm circumference (AOR=3.34, 95% CI:1.23,9.00), and monthly household income (AOR= 2.46, 95% CI: 1.05,5.72) were factors found to have a statistically significant association with the anemic status in the first trimester pregnant women. Conclusion: Considerable number of the study participants in this study had varying degrees of anemia. Therefore, we recommend healthcare providers strengthen their nutritional counseling services so as to get the dietary habits and nutritional status of the mothers corrected. Moreover, multi-sectorial (Agricultural, financial institutions, small scale industries and trade organizations) involvement is warranted to improve their economic status.